Epi-Guide^® is a uniquely structured, resorbable, synthetic membrane and is particularly suitable for use in periodontology.

Epi-Guide^® consists of a bioresorbable polymer, which is synthesized from D–, D–L, L– polylactic acid. The polymer is broken down to carbon dioxide and water. Epi-Guide^® is hydrophilic and has a patented multilayer architecture of different pore cavities. Its three–dimensional constructed density gradient is designed to attract and stabilize fibroblasts and epithelial cells. Acting as a space maker, it promotes the growth of bone and periodontal supporting tissue.

Epi-Guide^® organizes fibroblasts and epithelial cells so that epithelian migration during the later healing phase is blocked. The barrier function remains intact over more than six weeks; complete bioresorption occurs within approximately six to twelve months.

(The safety of polylactic acid was demonstrated in numerous studies in the field of toxicology and its in vitro and in vivo biocompatibility in several animal species and in human beings.

Polylactic acid (PLA) is an immunologically inert substance. Because of its biological and mechanical properties, PLA polymers have been used for years in diverse therapeutic settings, and they have demonstrated to be biocompatible, biologically resorbable and non-toxic. The slow biological resorbability renders a second procedure unnecessary.)

Tolerance of these materials both in the area of the bone and in the soft tissues is documented in many applications.